Fig. 3. (A) Schematic illustration of the AND gate. (B) Normalized fluorescence spectra of the AND gate. Inset: bar representation and Truth table of the AND gate. (C) Living cell analysis of different cell lines (in the form of FRET/FAM) using the designed AND gate to trace intracellular miRNAs in (a) MRC-5, (b) A549, (c) MCF-7, and (d) MDA-MB-231. All scale bars correspond to 20 μm. (D) Statistical histogram analysis of the above four different cells using the endogenous miRNA-initiated AND gate.
