Table 1. Demographic and clinical characteristics of participants.
| Characteristics | AD with apathy (n=66) | AD without apathy (n=66) | Statistics | |
|---|---|---|---|---|
| Age (yr) | 76.1±7.2 | 76.2±9.2 | t=−0.09; p=0.92 | |
| Sex (male/female) | 22/44 | 15/51 | χ2=1.84; p=0.18 | |
| Years of education (yr) | 5.9±4.5 | 5.6±4.3 | t=0.40; p=0.69 | |
| MMSE | 19.0±4.6 | 18.8±4.6 | t=0.28; p=0.78 | |
| CDR | χ2=0.33; p=0.57 | |||
| 0.5 | 48 | 45 | ||
| 1 | 18 | 21 | ||
| CDR-SOB | 3.3±1.9 | 3.1±2.0 | t=0.68; p=0.50 | |
| NPI | ||||
| Delusions | 0.6±1.7 | 0.9±2.3 | t=−0.64; p=0.52 | |
| Hallucinations | 0.4±1.3 | 0.6±2.0 | t=−0.63; p=0.53 | |
| Agitation | 0.9±1.4 | 1.1±2.2 | t=−0.75; p=0.45 | |
| Depression | 1.6±2.4 | 1.1±1.7 | t=1.33; p=0.18 | |
| Anxiety | 1.3±2.1 | 1.0±1.9 | t=0.81; p=0.42 | |
| Elation | 0.2±0.8 | 0.1±0.5 | t=1.05; p=0.30 | |
| Apathy | 4.3±3.1 | 0.0±0.0 | t=11.28; p<0.001 | |
| Disinhibition | 0.6±1.6 | 0.5±1.2 | t=0.12; p=0.90 | |
| Irritability | 1.8±2.4 | 1.4±2.1 | t=1.00; p=0.32 | |
| Aberrant motor behavior | 1.3±2.9 | 1.7±3.6 | t=−0.66; p=0.51 | |
| Sleep disorders | 1.8±3.0 | 1.5±2.9 | t=0.65; p=0.51 | |
| Eating disorders | 2.2±3.0 | 1.4±2.5 | t=1.51; p=0.13 | |
AD: Alzheimer's disease, MMSE: Mini-Mental State Examination, CDR: Clinical Dementia Rating, CDR-SOB: Clinical Dementia Rating-Sum of Boxes, NPI: Neuropsychiatric Inventory.