Table 2. Differences in regional cerebral blood flow between AD patients with apathy and those without apathy.

Regions		t	p	Coordinates* (x, y, z)	Cluster size (voxels)
AD with apathy > AD without apathy
	None
AD with apathy < AD without apathy
	L orbitofrontal cortex, putamen, nucleus accumbens, thalamus	3.47	<0.001	−6, 0, −10	557
	R insula	3.31	0.001	44, 4, 2	334
	L orbitofrontal cortex	3.27	0.001	−48, 26, −10	179
	L insula	3.07	0.001	−42, 4, 4	102
	R frontal pole, orbitofrontal cortex	2.92	0.002	46, 40, −12	121

AD: Alzheimer's disease, L: left, R: right.

^*The coordinates refer to the Montreal Neurological Institute coordinate system.