Table 1. Demographic data and means and standard deviations of K-MMSE, CDR, GDS, S-GDS, K-IADL, and BI.
Variables | Normal (n=254) | MCI | Dementia | F | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
MCI (n=673) | VaMCI (n=88) | PD-MCI (n=278) | F | Post hoc | AD (n=604) | VaD (n=131) | PDD (n=103) | F | Post hoc | |||
Sex§ (male/female) | 105/149 | 259/414 | 40/48 | 132/146 | 7.19* | 185/419 | 60/71 | 49/54 | 18.92‡ | 34.14‡ | ||
Age | 64.66±9.25 | 73.11±8.02 | 73.74±8.04 | 70.31±8.20 | 13.19‡ | aMCI=VaMCI>PD-MCI | 76.70±8.19 | 74.82±8.36 | 74.46±7.95 | 5.29† | AD>VaD=PDD | 69.96‡ |
Education (yr) | 9.88±4.02 | 9.51±5.29 | 7.61±5.19 | 9.03±5.49 | 5.19† | aMCI>VaMCI | 8.54±5.29 | 7.69±5.81 | 7.67±5.24 | 2.20 | 6.58‡ | |
PD-MCI=aMCI, VaMCI | ||||||||||||
K-MMSE | 27.99±1.89 | 24.72±3.55 | 25.05±3.65 | 25.29±3.48 | 2.31 | 18.80±4.58 | 19.02±4.34 | 20.17±4.47 | 2.27 | 246.50‡ | ||
CDR | - | 0.51±0.13 | 0.49±0.12 | 0.44±0.21 | 19.63‡ | aMCI=VaMCI>PD-MCI | 1.07±0.52 | 1.13±0.51 | 0.94±0.47 | 3.79* | AD=VaD>PDD | 217.21‡ |
GDS | - | 3.09±0.35 | 2.91±0.45 | 2.87±0.48 | 27.07‡ | aMCI>VaMCI=PD-MCI | 4.45±0.75 | 4.35±0.73 | 4.12±0.77 | 8.36‡ | AD=VaD>PDD | 482.36‡ |
S-GDS | 2.31±2.85 | 4.81±4.06 | 5.65±4.58 | 5.93±4.01 | 2.04 | 5.65±4.64 | 7.84±4.64 | 8.38±3.90 | 15.94‡ | AD<VaD=PDD | 24.53‡ | |
K-IADL | 0.05±0.12 | 0.20±0.21 | 0.20±0.22 | 0.20±0.26 | 0.28 | 1.23±0.75 | 1.29±0.66 | 1.03±0.66 | 3.78* | AD=VaD>PDD | 344.24‡ | |
BI | - | 19.79±1.19 | 19.38±2.65 | 19.33±2.26 | 10.60‡ | aMCI>VaMCI=PD-MCI | 18.72±2.65 | 17.26±3.90 | 17.21±3.84 | 22.58‡ | AD>VaD=PDD | 39.79‡ |
K-MMSE: Korean-Mini Mental State Examination, CDR: Clinical Dementia Raging, GDS: Global Deterioration Scale, S-GDS: short version of the Geriatric Depression Scale, K-IADL: Korean-Instrumental Activities of Daily Living, BI: Barthel Index, MCI: mild cognitive impairment, VaMCI: vascular mild cognitive impairment, PD-MCI: Parkinson's disease mild cognitive impairment, AD: Alzheimer's disease, VaD: vascular dementia, PDD: Parkinson's disease dementia, aMCI: amnestic mild cognitive impairment.
*p<0.05, †p<0.01, ‡p<0.001. §χ2 tests were used for sex ratio comparisons.