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. Author manuscript; available in PMC: 2019 Dec 18.
Published in final edited form as: Circulation. 2018 Dec 18;138(25):2895–2907. doi: 10.1161/CIRCULATIONAHA.118.035525

Figure 3A and 3B: Metformin Improves Insulin Sensitivity in Adolescents with Type 1 Diabetes.

Figure 3A and 3B:

Figure 3A. Change in M/I (per kg) in response to metformin vs. placebo, in all T1D participants, adjusted for baseline M/I (per kg) and change in M/I (per lean kg) in response to metformin vs. placebo in all T1D participants, adjusted for baseline M/I (per lean kg)

Figure 3B. Change in M/I (per kg) and M/I (per lean kg) in response to metformin vs. placebo in n=28 T1D youth with BMI <90th %ile, adjusted for baseline M/I (per kg) or baseline M/I (per lean kg)