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. 2019 Mar 13;11(5):1537–1550. doi: 10.18632/aging.101854

Table 3. Complications after hepatectomy for hepatocellular carcinoma.

Variables Total
(n=3386, 100%)
Age ≥ 80 y
(n=77, 2.3%)
Age < 80y
(n=3309, 97.7%)
p value
Any complications (n (%)) 1393(42.4) 46 (63.9) 1336 (41.6) 0.147
30-day mortality (n (%)) 61 (1.8) 3 (3.9) 58 (1.8) 0.162
In-hospital mortality (n (%)) 97 (2.9) 5 (6.5) 92 (2.8) 0.059
Mean hospital stay(days)a 11.25 ± 0.31 14.12 ± 1.89 11.15 ± 0.31 0.102
Surgical complications b Total
(n=278, 100%)
Age ≥ 80 y
(n=11, 4.0%)
Age < 80y
(n=267, 96.0%)
p value
Wound infection(n (%)) 9 (3.2) 0 (0) 9 (3.4) 0.536
Bile leakage (n (%)) 12 (4.3) 0 (0) 12 (4.5) 0.472
Post-OP bleeding requiring re-operation (n (%)) 1 (0.4) 0 (0) 1 (0.4) 0.839
Ascites requiring diuretics(n (%)) 82 (29.5) 5 (45.5) 77 (28.8) 0.236
Jaundice (n (%)) 2 (0.7) 0 (0) 2 (0.7) 0.773
Pleural effusion (n (%)) 5 (1.8) 1 (9.1) 4 (1.5) 0.184
Respiratory failure requiring intubation (n (%)) 2 (0.7) 1 (9.1) 1 (0.4) 0.078

a: mean ±standard error of mean; b: analysis performed on a subgroup of patients operated by a single surgeon between 2011 to 2015 (total patients: 278, Age ≥ 80 y: 11).