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. 2019 Mar 13;11(5):1537–1550. doi: 10.18632/aging.101854

Table 4. Risks factors for in-hospital mortality after hepatectomy for hepatocellular carcinoma in the octogenarian.

Variables Cases with in-hospital mortality (%) Odds ratio p value
Gender (male vs. female) 5 (8.6) vs. 0 (0) N.A.g 0.186
Diabetes mellitus (yes vs. no) 3 (9.4) vs. 2 (4.4) 2.224 0.387
Hypertension (yes vs. no) 2 (6.3) vs. 3 (7.7) 0.813 0.800
End-stage renal disease (yes vs. no) 0 (0) vs. 5 (6.8) N.A.g 0.588
Old stroke (yes vs. no) 0 (0) vs. 5 (7.5) N.A.g 0.571
Smoking (yes vs. no) 1 (7.7) vs. 4 (6.3) 1.250 0.847
Alcohol (yes vs. no) 0 (0) vs. 5 (7.1) N.A.g 0.498
HBs Aga (positive vs. negative) 2 (12.5) vs. 2 (3.8) 3.645 0.191
Hepatitis C virus (positive vs. negative) 2 (7.1) vs. 2 (5.4) 1.345 0.773
ICG-15b (> 10 vs. ≤ 10(%)) 2 (7.7) vs. 3 (8.6) 0.889 0.901
Hemoglobin (≤ 10 vs. > 10 (g/dL)) 1 (7.7) vs. 4 (6.3) 1.250 0.847
Albumin (≤ 3.5 vs. > 3.5 (g/dL)) 1 (5.0) vs. 3 (5.6) 0.894 0.925
Platelet (≤ 100 vs. > 100 (1000/uL)) 1 (10.0) vs. 4 (6.0) 1.751 0.630
INRc(> 1.4 vs. ≤ 1.4) 1 (100) vs. 4 (5.6) N.A.g <0.001
ALTd(> 40 vs. ≤ 40 (U/L)) 2 (6.5) vs. 3 (6.8) 0.943 0.950
Bilirubin total (> 1.5 vs. ≤ 1.5 (mg/dL)) 0 (0) vs. 4 (5.6) N.A.g 0.675
á-fetoprotein (> 200 vs. ≤ 200 (ng/mL)) 5 (21.7) vs. 0 (0) N.A.g 0.001
Procedure (major vs. minor (%))e 4 (16.7) vs. 1 (2.0) 9.804 0.019
OP duration (> 270 vs. ≤ 270 (min)) 3 (12.0) vs. 2 (3.9) 3.341 0.182
Blood loss (> 800 vs. ≤ 800 (mL)) 1 (6.7) vs. 4 (6.7) 1.000 1.000
Inflow control (yes vs. no) 3 (6.3) vs. 1 (8.3) 0.733 0.796
Tumor size (> 10 vs. ≤ 10 (cm)) 0 (0) vs. 5 (7.8) N.A.g 0.316
Surgical complications (major vs. minor/none)f 5 (25.0) vs. 0 (0) N.A.g <0.001

a: Hepatitis B virus surface antigen; b: Indocyanine green retention test at 15 min; c: International normalized ratio; d: Alanine aminotransferase; e: Major procedures include tri-segmentectomy, right/left lobectomy, and extended right/left lobectomy; f: Major surgical complications include grade III-IV surgical complications; g: not applicable or not done.