Table 3. Correlations between hormonal parameters and the levels of polyunsaturated fatty acids in BPH patients with and without MetS.
Variables | Patients with BPH and METS | Patients with BPH and without METS | |||||||||||||||
DHEA | E2 | SHBG | LH | TT | TF | IGF1 | I | DHEA | E2 | SHBG | LH | TT | TF | IGF1 | I | ||
C10:0 Capric acid | P | 0.055 | 0.132 | -0.273 | -0.014 | -0.151 | 0.367* | -0.263 | 0.036 | -0.038 | 0.039 | -0.125 | -0.212* | 0.010 | -0.004 | -0.024 | -0.128 |
p | 0.696 | 0.350 | 0.050 | 0.920 | 0.285 | 0.007 | 0.059 | 0.825 | 0.714 | 0.706 | 0.228 | 0.039 | 0.925 | 0.969 | 0.821 | 0.256 | |
C12:0 Lauric acid | P | 0.178 | -0.095 | -0.230 | 0.030 | -0.243 | -0.153 | -0.194 | 0.140 | 0.042 | 0.111 | -0.221* | -0.119 | -0.095 | -0.031 | -0.030 | 0.111 |
p | 0.207 | 0.501 | 0.101 | 0.833 | 0.083 | 0.279 | 0.168 | 0.383 | 0.689 | 0.288 | 0.032 | 0.255 | 0.360 | 0.767 | 0.775 | 0.329 | |
C14:0 Myristic acid | P | 0.068 | -0.046 | -0.378* | -0.003 | -0.267 | 0.082 | -0.213 | 0.062 | 0.125 | 0.147 | -0.272* | -0.096 | 0.004 | 0.088 | 0.063 | 0.191 |
p | 0.630 | 0.746 | 0.006 | 0.986 | 0.056 | 0.562 | 0.129 | 0.701 | 0.229 | 0.155 | 0.008 | 0.356 | 0.973 | 0.396 | 0.541 | 0.090 | |
C16:0 Palmitic acid | P | 0.183 | -0.032 | -0.329* | -0.025 | -0.308* | 0.160 | -0.137 | 0.049 | 0.166 | 0.058 | -0.141 | -0.091 | 0.125 | 0.150 | 0.153 | 0.060 |
p | 0.193 | 0.820 | 0.017 | 0.859 | 0.026 | 0.256 | 0.332 | 0.761 | 0.108 | 0.579 | 0.174 | 0.380 | 0.227 | 0.147 | 0.138 | 0.598 | |
C18:0 Stearic acid | P | 0.304* | -0.062 | -0.283* | -0.123 | -0.375* | 0.004 | -0.158 | -0.023 | 0.086 | -0.024 | -0.100 | -0.070 | 0.077 | 0.089 | 0.220* | 0.024 |
p | 0.028 | 0.660 | 0.042 | 0.385 | 0.006 | 0.975 | 0.263 | 0.885 | 0.409 | 0.819 | 0.337 | 0.500 | 0.457 | 0.389 | 0.032 | 0.832 | |
C18:1n9 cis/trans Oleic acid | P | 0.196 | 0.015 | -0.305* | 0.048 | -0.273 | 0.231 | -0.149 | 0.059 | 0.170 | 0.096 | -0.132 | -0.136 | 0.076 | 0.115 | 0.180 | 0.045 |
p | 0.165 | 0.915 | 0.028 | 0.733 | 0.050 | 0.100 | 0.293 | 0.714 | 0.099 | 0.355 | 0.202 | 0.189 | 0.464 | 0.267 | 0.082 | 0.694 | |
C18:1 trans vaccinic acid | P | 0.382* | -0.025 | -0.276* | -0.006 | -0.256 | 0.161 | -0.145 | 0.053 | 0.210* | 0.084 | -0.037 | -0.068 | 0.098 | 0.164 | 0.266* | 0.028 |
p | 0.005 | 0.861 | 0.048 | 0.968 | 0.067 | 0.254 | 0.304 | 0.744 | 0.042 | 0.416 | 0.725 | 0.515 | 0.347 | 0.113 | 0.009 | 0.807 | |
C18:2n6c Linolenic acid | P | 0.128 | -0.015 | -0.283* | -0.150 | -0.284* | 0.080 | -0.129 | -0.051 | 0.072 | -0.009 | -0.080 | -0.090 | 0.059 | 0.062 | 0.310* | -0.022 |
p | 0.365 | 0.915 | 0.042 | 0.290 | 0.041 | 0.573 | 0.363 | 0.751 | 0.487 | 0.931 | 0.443 | 0.385 | 0.573 | 0.548 | 0.002 | 0.848 | |
C18:3n6 gamma linolenic acid | P | 0.138 | -0.029 | -0.283* | 0.056 | -0.225 | 0.117 | -0.262 | -0.020 | -0.005 | 0.127 | -0.213* | 0.003 | 0.037 | 0.073 | -0.004 | 0.053 |
p | 0.328 | 0.839 | 0.042 | 0.693 | 0.109 | 0.411 | 0.060 | 0.900 | 0.965 | 0.220 | 0.038 | 0.978 | 0.720 | 0.484 | 0.967 | 0.643 | |
C18:3n3 linolenic acid | P | 0.020 | -0.002 | -0.314* | -0.131 | -0.289* | 0.117 | -0.122 | 0.041 | 0.002 | 0.009 | -0.130 | -0.111 | -0.176 | -0.040 | 0.213* | 0.009 |
p | 0.890 | 0.987 | 0.024 | 0.356 | 0.038 | 0.409 | 0.390 | 0.798 | 0.982 | 0.929 | 0.208 | 0.283 | 0.088 | 0.700 | 0.038 | 0.933 | |
C20:0 Arachidic acid | P | -0.109 | 0.183 | -0.244 | -0.013 | -0.322* | <0.001 | -0.155 | 0.173 | -0.069 | -0.044 | -0.122 | 0.025 | -0.139 | -0.098 | -0.077 | -0.131 |
p | 0.467 | 0.218 | 0.099 | 0.932 | 0.027 | 0.998 | 0.298 | 0.306 | 0.569 | 0.717 | 0.310 | 0.834 | 0.249 | 0.418 | 0.524 | 0.311 | |
C22:1 cis11- eicosenic acid | P | 0.316* | 0.082 | -0.243 | -0.082 | -0.285* | 0.193 | -0.189 | 0.058 | 0.210* | -0.024 | -0.129 | 0.016 | -0.026 | 0.121 | 0.247* | -0.042 |
p | 0.023 | 0.564 | 0.083 | 0.564 | 0.040 | 0.171 | 0.181 | 0.719 | 0.041 | 0.816 | 0.213 | 0.881 | 0.805 | 0.242 | 0.016 | 0.710 | |
C20:2 cis-11-eicosadienoic acid | P | 0.317* | -0.138 | -0.234 | -0.049 | -0.256 | -0.012 | -0.188 | 0.032 | 0.192 | -0.032 | -0.062 | -0.084 | 0.082 | 0.162 | 0.217* | 0.113 |
p | 0.023 | 0.335 | 0.099 | 0.734 | 0.070 | 0.931 | 0.188 | 0.842 | 0.067 | 0.765 | 0.557 | 0.428 | 0.437 | 0.123 | 0.038 | 0.326 | |
C20:3n6 eicosatrienoic acid | P | 0.294* | 0.048 | -0.307* | -0.080 | -0.366* | 0.021 | -0.155 | 0.044 | 0.117 | -0.029 | -0.126 | -0.106 | 0.057 | 0.145 | 0.166 | 0.107 |
p | 0.035 | 0.734 | 0.027 | 0.572 | 0.008 | 0.885 | 0.274 | 0.782 | 0.258 | 0.783 | 0.225 | 0.309 | 0.583 | 0.162 | 0.109 | 0.344 | |
C20:4n6 Arachidonic acid | P | 0.305* | 0.056 | -0.284* | -0.181 | -0.307* | 0.132 | -0.132 | 0.018 | 0.034 | 0.036 | -0.089 | -0.027 | 0.081 | 0.005 | 0.205* | -0.049 |
p | 0.028 | 0.693 | 0.042 | 0.200 | 0.027 | 0.351 | 0.352 | 0.912 | 0.744 | 0.731 | 0.390 | 0.793 | 0.438 | 0.958 | 0.047 | 0.663 | |
C20:5n3 EPA | P | -0.038 | 0.143 | -0.089 | -0.349* | -0.172 | 0.061 | -0.103 | 0.068 | -0.025 | 0.008 | -0.198 | 0.291* | -0.113 | -0.046 | 0.014 | 0.057 |
p | 0.789 | 0.311 | 0.531 | 0.011 | 0.224 | 0.668 | 0.468 | 0.671 | 0.808 | 0.941 | 0.054 | 0.004 | 0.276 | 0.655 | 0.896 | 0.618 | |
C22:5w3 (docosapentaenate) | P | 0.241 | 0.044 | -0.082 | -0.172 | -0.169 | 0.179 | -0.207 | 0.024 | 0.131 | <0.001 | -0.092 | -0.052 | 0.078 | 0.120 | 0.139 | -0.036 |
p | 0.086 | 0.755 | 0.562 | 0.221 | 0.230 | 0.205 | 0.140 | 0.880 | 0.206 | 0.999 | 0.376 | 0.615 | 0.451 | 0.248 | 0.180 | 0.753 | |
C22:6n3 DHA | P | 0.236 | 0.016 | -0.081 | -0.275* | -0.152 | 0.096 | -0.013 | -0.061 | -0.086 | -0.028 | -0.192 | 0.174 | -0.150 | -0.095 | 0.208* | 0.076 |
p | 0.092 | 0.910 | 0.567 | 0.048 | 0.282 | 0.498 | 0.926 | 0.705 | 0.407 | 0.786 | 0.062 | 0.091 | 0.146 | 0.359 | 0.043 | 0.500 | |
LTX A4 5S, 6R, 15R | P | -0.048 | 0.115 | -0.221 | 0.035 | -0.148 | -0.041 | -0.097 | 0.422* | -0.034 | -0.077 | -0.351* | -0.136 | -0.202 | -0.062 | -0.046 | 0.009 |
p | 0.738 | 0.417 | 0.115 | 0.807 | 0.294 | 0.775 | 0.495 | 0.006 | 0.745 | 0.462 | 0.001 | 0.190 | 0.051 | 0.551 | 0.660 | 0.935 | |
LTX A4 5S, 6R | P | -0.083 | 0.055 | -0.259 | 0.065 | -0.153 | -0.083 | -0.092 | 0.239 | -0.007 | -0.025 | -0.348* | -0.130 | -0.184 | -0.031 | -0.048 | 0.045 |
p | 0.559 | 0.701 | 0.064 | 0.647 | 0.279 | 0.560 | 0.515 | 0.132 | 0.945 | 0.808 | 0.001 | 0.213 | 0.076 | 0.767 | 0.648 | 0.691 |
(BPH, benign prostatic hyperplasia; METS, metabolic syndrome; p, statistical significance; P, correlation coefficient; TT, total testosterone; TF, free testosterone; SHBG, sex hormone binding globulin; E2, estradiol; DHEAs, dehydroepiandrosterone sulfate; LH, luteinizing hormone; IGI-1, insulin like grow factor-1; I, insulin; *, statistical significant parameter)