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. 2019 Mar 5;11(5):1456–1470. doi: 10.18632/aging.101845

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Copyright © 2019 Chu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY) 3.0 License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Inhibitory effects of LINC00657 on GBM tumor growth was reversed by VO-Ohpic. (A) Cell viability of LN-18 and U-118MG after transfecting with pcDNA3.1-LINC00657 with or without VO-Ohpic (100 nM) for 48 h was detected CCK-8 assay. (B) Cell apoptosis of LN-18 and U-118MG was detected with flow cytometry. (C) Apoptosis rate of LN-18 and U-118MG. (D) The protein level of p-Akt in GBM cells after transfecting with pcDNA3.1-LINC00657 with or without VO-Ohpic for 48 h was measured with western blot. (E) Relative p-Akt levels in the cells. **P<0.01.