Table 2. Univariate and multivariate analysis for OS in patients with CRC.
| Characteristics | Multivariate analysis for OS | Univariate analysis for OS | ||
| HR (95% CI) | HR (95% CI) | |||
| Age (<60/≥60) | - | - | 1.023(0.681-1.232) | 0.332 |
| Gender (Female/Male) | - | - | 0.909(0.616-1.331) | 0.215 |
| Tumor location (colon/rectum) | - | - | 0.918(0.661-1.421) | 0.571 |
| Tumor size (<5/≥5cm) | - | - | 0.911(0.751-1.434) | 0.314 |
| Differentiation (well/moderate/poor) | 1.878 (1.212-3.132) | 0.019 | 3.125(2.019-5.111) | 0.007 |
| CEA (<10/≥10ng/mL) | - | - | 0.799(0.516-1.114) | 0.261 |
| Location invasion (T1+T2/T3+T4) | - | - | 1.091(0.781-1.298) | 0.315 |
| Lymph node metastasis (N0-N1/N2) | 1.516(1.093-2.978) | 0.012 | 1.902(1.311-3.391) | 0.006 |
| TNM stage (I-II/III-IV) | 1.742 (1.065-3.145) | 0.002 | 3.289 (2.141-4.995) | <0.001 |
| TINCR (low/high) | 0.459 (0.265-0.912) | 0.027 | 0.414(0.226-0.624) | 0.005 |
Abbreviations: CI, confidence interval; HR, hazard ratio.