Table 1. Characteristics of the study population.
| Variable | ME/CFS (n = 14) | Control (n = 11) | P Value |
|---|---|---|---|
| Age in years, median (IQR) | 49 (38, 58.3) | 50 (45.5, 58.5) | 0.6216 |
| BMI, median (IQR) | 26.63 (21.4, 34.9) | 26.45 (24.1, 35.2) | 0.7675 |
| Core Symptoms, n (%) | |||
| Fatigue | 14 (100) | 1 (9) | < .00001 |
| Pain | 14 (100) | 3 (27) | < .001 |
| Post Exertional Fatigue | 14 (100) | 1 (9) | < .00001 |
| Karnofsky Score Last 7 Days | 60 (56.25, 68.75) | 100 (90, 100) | < .0001 |
| Functional Capacity Last 7 Days | 4 (3, 5.75) | 8 (7.75, 8) | < .0001 |
| Illness Onset Pattern n (%) | |||
| Gradual | 9 (64) | NA | NA |
| Sudden | 5 (36) | NA | NA |
| History of Infection at Onset | 9 (64) | NA | NA |
| Illness duration yrs, median (IQR) | 5.75 (5, 7.5) | NA | NA |
| Baseline 5 Day Accelerometry, Median(IQR) | |||
| Wear Time (% of time) | 90.5 (89, 94) | 95 (93, 96) | 0.1958 |
| Steps in 5 Days | 28447(15722,33186) | 32995 (20940,50688) | 0.2671 |
| Activity Distribution (% of time) | |||
| Sedentary | 78.4 (71,81.5) | 74.5 (71.1,77.2) | 0.3111 |
| Light | 21.05 (18,26) | 22.8 (20.5,24.6) | 0.5719 |
| Moderate | 1.1 (0.3,2.1) | 1.3 (0.8,4.2) | 0.2612 |
| Vigorous | 0.0 (0, 0) | 0.0 (0, 0) | 0.8084 |
| Sleeping (Hours of Sleep Per 24 Hours) | 6.7 (5.9, 7.9) | 7.3 (6.2, 7.9) | 0.4593 |
| Awakenings (Per 24 Hours) | 5.8 (4.6,6.9) | 8.2 (5.3, 10) | 0.0708 |
Values are presented as median (IQR). P values were calculated with Wilcoxon rank-sum test. Statistically significant values (p < 0.05) were denoted in bold.