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. 2019 Mar 11;13(3):e0007250. doi: 10.1371/journal.pntd.0007250

Table 1. LD50 values from Micrurus venoms studied herein, compared with literature data.

Micrurus species
Source dumerilii mipartitus isozonus surinamensis medemi lemniscatus spixii
This study 23.72 33.62 6.29 29.17 8.79 22.87 13.89
(18.09–31.12) (26.15–43.22) (5.14–7.69) (24.42–34.84) (7.16–10.80) (17.79–29.4) (N.D.)
Bolaños et al. [37] 17.00 - - 5−10 - 5* 10−15*
(N.S.) (N.S.) (N.S.) (N.S.)
Tanaka et al.[16] - - 58** - 13** 8**
(43–87) (7–22) (6–16)
Silva[38] - - 9.43 - 10.12 50.6
(N.S.) (N.S.) (N.S.)
Cohen [14] 16.3 - - - - - 27.3***
(N.S.) (N.S.)
Cohen[13] 11.9 - - - - - -
(N.S.)
Rey-Suarez et al. [23] 22.42 - - - - - -
(14.5–36–1)
Otero et al. [39] - 9 - - - - -
(6.6–9.1)
Oliveira et al. [40] - - - 14** - - -
(11.3–16.8)
de Roodt et al. [26] - - - 7.6 - - -
(5–19)
de Roodt et al. [41] - - - 20 - - -
(N.S.)
Salazar et al. [42] - - 11.4 - - - -
(N.S.)
Higashi et al. [15] - - - - - - 6.7**
(N.S.)
Max/Min ratio 1.99 3.74 1.81 11.60 - 4.57 7.55

Values are given in μg/mice (see Materials and Methods for details). 95% confidence intervals are indicated in parenthesis. N.D., not determined because, on the trial doses, only death ratios corresponding to 0% and 100% were recorded; N.S., not specified on the study. Data without asterisk marks correspond to venoms from Colombia;

*unknown origin;

** Brazil;

*** Peru.