Table 3. Final multivariable model: Predictors of TBS in HIV positive subjects in the HIV UPBEAT cohort.
| Co-variates | Effect on TBS | 95% C.I | P |
|---|---|---|---|
| LS BMD ((per 1g/cm2 increase) | 0.002 | 0.001, 0.003 | <0.001 |
| Age (per 5 years increase) | -0.018 | -0.027, -0.009 | 0.002 |
| Gender (Male v Female) | -0.004 | -0.044, 0.034 | 0.81 |
| Ethnicity (African versus non-African | 0.035 | -0.009, 0.070 | 0.16 |
| Current smoker | -0.047 | -0.085, -0.008 | 0.017 |
| Nadir CD4 T–cell count (per 50cells/mm) | 0.005 | 0.0003, 0.011 | 0.040 |
| On PI at baseline | -0.045 | -0.079, -0.011 | 0.009 |
Table 3 Legend: HIV-related variables were added stepwise with predictors of TBS included in the subsequent steps in building the final model; this represents the final model which best predicts lower TBS in HIV.
LS BMD—Lumbar spine BMD, TBS—Trabecular bone score, C.I—Confidence Interval, IVDU—Intravenous drug use, PI—Protease inhibitor