Table 2.

Characteristics of GPs and patients in the clinical vignette associated with the choices of prescribing or continuing various analgesic medicines, despite the GPs’ negative evaluation of their risk–benefit ratios (logistic regressions, results of backward selection)

	Paracetamol and tramadol (n = 1168)		Amitriptyline (n = 1183)		NSAID (ketoprofen) (n = 1183)
Variables	AOR (95% CI)	P-value	AOR (95% CI)	P-value	AOR (95% CI)	P-value
Stratification variables
Age (ref <50 years)
50–58 years	0.77 (0.54 to 1.12)	0.17	0.85 (0.57 to 1.26)	0.41	0.91 (0.65 to 1.26)	0.57
>58 years	0.73 (0.47 to 1.13)	0.16	0.89 (0.56 to 1.43)	0.64	1.65 (1.16 to 2.36)	0.006
Sex (ref Male)
Female	1.13 (0.80 to 1.61)	0.48	1.28 (0.88 to 1.86)	0.20	0.87 (0.64 to 1.18)	0.37
Workload (ref <3067 consultations and visits)
3067–6028	1.22 (0.79 to 1.89)	0.36	1.42 (0.88 to 2.27)	0.15	1.05 (0.73 to 1.51)	0.80
>6028	1.26 (0.77 to 2.06)	0.36	1.21 (0.70 to 2.11)	0.49	0.93 (0.61 to 1.41)	0.73
GP density of the municipality of practice (ref < −19.3% of the national average)
−19.3% to +17.7% of the national average	0.72 (0.50 to 1.04)	0.08	1.14 (0.75 to 1.72)	0.54	0.86 (0.62 to 1.18)	0.35
> +17.7% of the national average	0.75 (0.48 to 1.17)	0.20	1.28 (0.79 to 2.07)	0.32	1.03 (0.71 to 1.50)	0.86
Professional characteristics
Practice of complementary medicine (for example, homeopathy, acupuncture) (ref ‘No’)
Yes	1.62 (1.01 to 2.58)	0.04	NR		NR
Reported proportion of patients with multimorbidity on GP’s list (ref <25%)
25–50%	0.98 (0.70 to 1.37)	0.90	NR		NR
>50%	0.51 (0.28 to 0.92)	0.02	NR		NR
Patients’ characteristics
Age, years (ref 54 years)
82	NR		NR		0.48 [0.36 to 0.63]	<0.001
History of stroke (ref ‘No’)
Yes	NR		0.63 [0.45 to 0.90]	0.01	0.55 [0.42 to 0.72]	<0.001

AOR = adjusted odds ratio. NR = not retained in the backward selection procedure. NSAID = non-steroidal anti-inflammatory drug. Ref = reference.