Table 3.
The Mean Percentage of WiDr Cells that Develop Apoptosis after Incubation for 24 h with Various Concentrations of PNF
| Treatment | Concen-tration µg/mL | % of living cell (LL) | % of early apoptotic stage (LR) | % of late apoptotic stage and early necrosis (UR) | % of late necrosis (UL) | % of totally apoptotic cells (LR+UR) |
|---|---|---|---|---|---|---|
| Cell control | 0 | 95.20 ± 0.17 | 2.20 ± 0.49 | 2.30 ± 0.27 | 0.30 ± 0.12 | 4.5 |
| Polyiso-prenoids from N. fruticans | 18 (1/10 IC50) | 92.90 ± 0.13 | 1.70 ± 0.29 | 4.60 ± 0.32 | 0.80 ± 0.46 | 6.3 |
| 36 (1/5 IC50) | 95.50 ± 0.16 | 2.20 ± 0.31 | 2.00 ± 0.29 | 0.30 ± 0.29 | 4.2 | |
| 90 (1/2 IC50) | 27.00 ± 0.37 | 16.00 ± 0.43 | 52.70 ± 0.47 | 4.30 ± 0.23 | 68.7 | |
| 180 (1 IC50) | 36.60 ± 0.27 | 29.60 ± 0.24 | 30.70 ± 0.29 | 3.10 ± 0.32 | 60.3 |
Data were expressed as mean ± SD (n=3)