Table 2.
Univariate and Multivariate Analysis of Predictors of Microvascular Invasion
| Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
| OR (95% CI) | p value | OR (95% CI) | p value | |
| Age (years) | 0.992 (0.96–1.02) | 0.535 | ||
| INR | 0.418 (0.04–4.15) | 0.457 | ||
| AFP (<400 ng/mL) | ||||
| >400 ng/mL | 1.557 (0.91–2.65) | 0.102 | ||
| PLR (<102) | ||||
| >102 | 2.385 (1.39–4.07) | 0.001 | 1.831(1.05–3.21) | 0.034 |
| PNI (<95) | ||||
| >95 | 0.736 (0.43–1.25) | 0.259 | ||
| NLR (<1.8) | ||||
| >1.8 | 1.167 (0.96–1.42) | 0.121 | ||
| Tumor size (<5cm) | ||||
| >5 cm | 4.299 (2.41–7.66) | 0 | 3.791(2.1–6.84) | 0 |
| Gender (Male) | ||||
| Female | 1.202 (0.70–2.06) | 0.502 | ||
| HBV (Negative) | ||||
| Positive | 0.702 (0.42–1.18) | 0.182 | ||
| HCV (Negative) | ||||
| Positive | 1.224 (0.64–2.35) | 0.543 | ||
| Alcohol (None) | ||||
| Occasional | 1.405 (0.74–2.68) | 0.302 | ||
| Alcoholism | 1.203 (0.60–2.40) | 0.599 | ||
| Child–Pugh score (A) | ||||
| B | 1.193 (0.37–3.82) | 0.767 | ||
| Multifocal tumor (Single) | ||||
| zMultiple | 1.233 (0.68–2.25) | 0.492 | ||
AFP, alpha-fetoprotein; CI, confidence interval; HBV, hepatitis B virus; HCV, hepatitis C virus; INR, international normalized ratio; NLR, neutrophil-to-lymphocyte ratio; OR, odds ratio; PLR, platelet-to-lymphocyte ratio; PNI, prognostic nutritional index.