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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: Expert Opin Drug Metab Toxicol. 2019 Mar 18;15(4):329–339. doi: 10.1080/17425255.2019.1588884

Table 2:

Disease onsets that were shown to regulate EST expression within different species.

DISEASE STATE EST REGULATION SPECIES REFERENCES
Endometrial Cancer Downregulated Human [83]
Ovarian Cancer Downregulated Human [85]
Breast Cancer Downregulated Human [86]
Endometriosis Downregulated Human [89]
Metabolic Disease Upregulated Mouse [96]
Sepsis Upregulated Mouse [98]
Ischemia-Reperfusion Upregulated Mouse [99]
Cystic Fibrosis Upregulated Mouse [105]