Table 2.
Nucleotide concentrations in SS and IS samples.
| SS Mean ± SD (n) | IS Mean ± SD (n) | Sample Type p valueƚ | Significant Covariatesǂ | |
|---|---|---|---|---|
| ADO | 321.0 ± 408.4 (51) | 276.0 ± 375.0 (76) | 0.256 | current Smoking p=0.002 |
| AMP | 2796.3 ± 4382.9 (54) | 1745.2 ± 2762.3 (76) | 0.091 | ICS Use p=0.042 |
| ADP | 704.2 ± 682.4 (54) | 602.6 ± 575.4 (76) | 0.277 | none |
| ATP | 376.3 ± 499.1 (54) | 280.3 ± 366.1 (76) | 0.111 | none |
| Total | 3814.7 ± 3263.0 (51) | 2904.3 ± 3050.6 (76) | 0.085 | none |
*
Four subjects data was eliminated because of one or more nucleotide values >5 times the mean
ƚ
Significance determined in a mixed model
ǂ
Covariates included sample type, age, race, sex, current smoking, pack years,
FEV1 % Predicted, month of visit and ICS use