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. Author manuscript; available in PMC: 2019 Mar 21.
Published in final edited form as: Mol Psychiatry. 2018 Sep 21;25(6):1344–1354. doi: 10.1038/s41380-018-0247-6

Figure 1:

Figure 1:

In this study we present a three-phase, multi-tissue design: Top) a Discovery Phase involving a MWAS in a large set of blood samples as well as a number of exploratory analysis; Middle) an Overlap Phase where we test for enrichment of MWAS overlap between blood and brain; Bottom) a Replication Phase where all sites in the significant overlap are followed up with “look-up replication” in two independent brain collections from BA10 and in the second brain tissue (BA25) from the original brain MWAS sample.