. Author manuscript; available in PMC: 2020 May 1.

Published in final edited form as: Eur J Pharm Biopharm. 2018 May 24;138:23–29. doi: 10.1016/j.ejpb.2018.05.030

Table 4.

Fold changes in colon TFV-DP AUC_last when comparing various enema formulations. Values in the table represent the fold increase when comparing row > column. N/A represents redundant comparisons that are omitted for clarity.

	TDF/NaHCO₃	TFV/NaOH	TAF	CMX
TFV/NaHCO₃	3.8^*	7.5^*	30^*	256^*
TDF/NaHCO3	N/A	2.0	7.9^*	68^*
TFV/NaOH	N/A	N/A	4.0^*	34^*
TAF	N/A	N/A	N/A	8.5^*

p < 0.05