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. 2019 Feb 7;53(2):1801193. doi: 10.1183/13993003.01193-2018

TABLE 2.

Prevalence of chronic obstructive pulmonary disease (COPD) and respiratory symptoms

Lowlands Highlands p-value
Subjects 193 199
Post-BD FVC % pred 92.0 (84.0–104.0) 100.0 (92.0–110.0) <0.001
Post-BD FEV1 % pred 90.0 (83.0–101.5) 92.0 (85.0–104.0) 0.091
Post-BD FEV1/FVC % 82.0 (75.0–96.0) 76.0 (65.0–97.0) 0.003
COPD 20 (10.4) 73 (36.7) <0.001
 Male 16 (80.0) 36 (49.3) <0.001
 Moderate/severe (GOLD stage ≥2) 14 (70.0) 18 (24.7) <0.001
SpO2 % 95.0 (95.0–96.0) 93.0 (92.0–95.0) <0.001
Chronic cough/sputum# 15 (7.8) 47 (23.6) <0.001
Severe breathlessness (MRC dyspnoea scale ≥4) 6 (3.1) 22 (11.1) 0.003

Data are presented as n, median (interquartile range) or n (%). Missing outcomes for lung function were excluded from the study (figure 1); there were no other missing values. BD: bronchodilation; FVC: forced vital capacity; FEV1: forced expiratory volume in 1 s; GOLD: Global Initiative for Chronic Obstructive Lung Disease; SpO2: arterial oxygen saturation measured by pulse oximetry; MRC: Medical Research Council. #: chronic is defined as having symptoms for ≥2 months.