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. Author manuscript; available in PMC: 2020 Mar 5.
Published in final edited form as: Circulation. 2019 Mar 5;139(10):1275–1284. doi: 10.1161/CIRCULATIONAHA.118.036675

Table 2.

Unadjusted Odds Ratios (95% Confidence Intervals) of Uncontrolled or Resistant Hypertension Versus Controlled Hypertension

Variable Uncontrolled (n=320) Resistant (n=96)
Odds Ratio (95% CI) P Value Odds Ratio (95% CI) P Value
REI4%* ≥15 vs REI4% <15 1.10 (0.74–1.62) 0.64 1.92 (1.15–3.20) 0.01
Sleep apnea (4%)
Mild sleep apnea vs none (4%) 0.84 (0.58–1.24) 0.39 1.65 (0.93–2.93) 0.09
Moderate sleep apnea vs none (4%) 0.94 (0.57–1.53) 0.79 1.83 (0.90–3.70) 0.09
Severe sleep apnea vs none (4%) 1.12 (0.58–2.17) 0.74 3.50 (1.54–7.91) 0.003
P trend 0.99 0.003
Percent time in hypoxemia 1.03 (0.82–1.28) 0.82 1.30 (1.05–1.61) 0.01
Age (per 10 y) 0.81 (0.69–0.95) 0.01 1.21 (0.96–1.52) 0.11
Male (yes vs no) 1.34 (0.93–1.93) 0.12 1.35 (0.81–2.25) 0.25
Education 1.08 (0.92–1.28) 0.35 0.76 (0.61–0.95) 0.02
Obese (yes vs no) 1.01 (0.72–1.42) 0.93 1.10 (0.68–1.78) 0.70
Diabetes (yes vs no) 0.53 (0.36–0.77) 0.001 1.14 (0.70–1.86) 0.61
Current/past smoker (yes vs no) 1.14 (0.79–1.63) 0.49 0.81 (0.48–1.37) 0.44
Depressive symptoms 1.00 (0.98–1.02) 0.98 1.04 (1.01–1.07) 0.007
Perceived stress 1.01 (0.99–1.04) 0.31 1.04 (1.00–1.07) 0.04
Sleep duration, min 1.00 (1.00–1.00) 0.22 1.00 (1.00–1.00) 0.74
Sleep efficiency, % 1.00 (0.96–1.03) 0.92 0.99 (0.94–1.04) 0.78
*

4% oxygen desaturation. Percent time in hypoxemia was standardized to a mean of 0 and standard deviation of 1. The referent group is controlled hypertension (n=248).