Table 2.
Variable | Uncontrolled (n=320) | Resistant (n=96) | ||
---|---|---|---|---|
Odds Ratio (95% CI) | P Value | Odds Ratio (95% CI) | P Value | |
REI4%* ≥15 vs REI4% <15 | 1.10 (0.74–1.62) | 0.64 | 1.92 (1.15–3.20) | 0.01 |
Sleep apnea (4%) | ||||
Mild sleep apnea vs none (4%) | 0.84 (0.58–1.24) | 0.39 | 1.65 (0.93–2.93) | 0.09 |
Moderate sleep apnea vs none (4%) | 0.94 (0.57–1.53) | 0.79 | 1.83 (0.90–3.70) | 0.09 |
Severe sleep apnea vs none (4%) | 1.12 (0.58–2.17) | 0.74 | 3.50 (1.54–7.91) | 0.003 |
P trend | 0.99 | 0.003 | ||
Percent time in hypoxemia | 1.03 (0.82–1.28) | 0.82 | 1.30 (1.05–1.61) | 0.01 |
Age (per 10 y) | 0.81 (0.69–0.95) | 0.01 | 1.21 (0.96–1.52) | 0.11 |
Male (yes vs no) | 1.34 (0.93–1.93) | 0.12 | 1.35 (0.81–2.25) | 0.25 |
Education | 1.08 (0.92–1.28) | 0.35 | 0.76 (0.61–0.95) | 0.02 |
Obese (yes vs no) | 1.01 (0.72–1.42) | 0.93 | 1.10 (0.68–1.78) | 0.70 |
Diabetes (yes vs no) | 0.53 (0.36–0.77) | 0.001 | 1.14 (0.70–1.86) | 0.61 |
Current/past smoker (yes vs no) | 1.14 (0.79–1.63) | 0.49 | 0.81 (0.48–1.37) | 0.44 |
Depressive symptoms | 1.00 (0.98–1.02) | 0.98 | 1.04 (1.01–1.07) | 0.007 |
Perceived stress | 1.01 (0.99–1.04) | 0.31 | 1.04 (1.00–1.07) | 0.04 |
Sleep duration, min | 1.00 (1.00–1.00) | 0.22 | 1.00 (1.00–1.00) | 0.74 |
Sleep efficiency, % | 1.00 (0.96–1.03) | 0.92 | 0.99 (0.94–1.04) | 0.78 |
4% oxygen desaturation. Percent time in hypoxemia was standardized to a mean of 0 and standard deviation of 1. The referent group is controlled hypertension (n=248).