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. Author manuscript; available in PMC: 2020 Mar 5.
Published in final edited form as: Circulation. 2019 Mar 5;139(10):1275–1284. doi: 10.1161/CIRCULATIONAHA.118.036675

Table 3.

Odds Ratios (95% Confidence Intervals) of Uncontrolled or Resistant Hypertension Versus Controlled Hypertension Associated With Moderate or Severe Sleep Apnea and Percent Time in Hypoxemia

Uncontrolled (n=320) Resistant (n=96)
Odds Ratio (95% CI) P Value Odds Ratio (95% CI) P Value
REI4%* ≥15 vs. REI4% <15
Model 1 1.10 (0.74–1.62) 0.64 1.92 (1.15–3.20) 0.01
Model 2 1.09 (0.71–1.66) 0.70 1.85 (1.06–3.21) 0.03
Model 3 1.09 (0.70–1.69) 0.71 2.04 (1.14–3.67) 0.02
Percent time in hypoxemia
Model 1 1.03 (0.82–1.28) 0.82 1.30 (1.05–1.61) 0.01
Model 2 1.02 (0.82–1.27) 0.87 1.27 (1.03–1.58) 0.03
Model 3 1.01 (0.81–1.27) 0.92 1.25 (1.01–1.55) 0.04

Model 1: Unadjusted. Model 2: Adjusted for age, sex, obese, education, smoking, and diabetes mellitus. Model 3: Adjusted for age, sex, obese, education, smoking, diabetes, depressive symptoms, perceived stress, sleep duration, and sleep efficiency.

*

4% oxygen desaturation. Percent time in hypoxemia was standardized to a mean of 0 and standard deviation of 1. The referent group is controlled hypertension (n=248).