Table 2.

Main differences for group comparisons and covariance analyses done at baseline between healthy controls (HC) and Parkinson’s disease patients (PD).

Analysis	Region	Coordinates (mm)			T-value	Cluster size
		x	y	z
FA maps: PD > HC	Left pontine tegmentum	−8	−21	−21	4.7	163
	Right pontine tegmentum	9	−22	−22	4.5	167
MD maps: PD > HC	Right operculum	58	9	−2	5	1571
Covariance DAT-MD: PD > HC	Pons nuclei	4	−26	−28	4	884
Covariance DAT-GM volume: PD > HC	Left prefrontal cortex	−44	20	34	4.6	681
	Left premotor cortex	−8	6	39	4.5	607
	Left insula	−54	−14	16	4	625
	Right insula	58	−12	14	4	686