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. 2019 Feb 5;10(1):e02765-18. doi: 10.1128/mBio.02765-18

TABLE 1.

Candidates for gene deletion

Gene ID Secretion
prediction
TMHMMa Predicted domain (Pfam
or InterPro accession no.)
Putative protein homolog (reference)
(% identity; alignment score; E value)
atf1 190180 No None bZIP_1 (PF00170) Atf1 (45) (30.4; 200; 1.4e−15)
atf2 156289 No None bZIP_1 (PF00170) Atf1 (45) (31.1; 180; 5.7e−14)
gcn4 85517 No None bZIP_1 (PF00170) GCN4 (62) (50; 100; 1.4e−3)
pps1 115037 Yes None None predicted MP88 (40) (29; 190; 7e−17)
aqp1 167023 Yes 6 Aquaporin-like (IPR023271) AQY1 (63) (32; 309; 3.7e−31)
chi1 189685 NCSb None None predicted None
igp1 154866 Yes None None predicted None
ico1 155573 Yes None Isochorismatase (PF00857) YcaC (64) (61.9; 655; 2.2e−84)
a

TMHMM, Transmembrane Helix Prediction based on a hidden Markov Model.

b

Putative secretion by noncanonical secretion (NCS) pathway.