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. 2019 Mar 15;13:50. doi: 10.3389/fnbeh.2019.00050

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Copyright © 2019 Murata, Kinoshita, Fukazawa, Kobayashi, Yamanaka, Hikida, Manabe and Yamaguchi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Summary diagram. Both D1 and D2 neurons are intermingled in the anteromedial OT. Both cell types project their axons mainly to the pallidum, hypothalamus, amygdala, and midbrain. Cell type-specific activation using optogenetics revealed the opposing roles of the D1 and D2 neurons in the anteromedial OT in eliciting attractive and aversive behaviors, respectively. OT, olfactory tubercle; D1 neuron, dopamine receptor D1-expressing neuron; D2 neuron, dopamine receptor D2-expressing neuron. Stereotaxic atlas from Franklin and Paxinos (2008).