Fig. 2.

CARTBox2 workflow. a The preprocedural steps include the acquisition of an LGE-MRI scan of the left ventricle. The endocardium, epicardium and infarct are then segmented. Using CARTBox2, from these segmentations, the scar transmurality is calculated and projected onto the endocardial surface mesh. Subsequently, the IBZ is calculated and the injection locations are defined and projected onto the mesh (brown arrows), these locations are embedded into the MRI DICOM images. b After acquiring a 3D-RA scan, the MRI DICOM image is fused with the 3D-RA image based on skeletal anatomy. During the injection procedure, the target locations are visualized on the live fluoroscopic images. The AP and RAO images showing the endocardium (red) and target (blue) are visually enhanced for printing purposes. LGE-MRI late gadolinium enhanced magnetic resonance image, IBZ infarct border zone, 3D-RA 3-dimensional rotational angiography, AP anterior-posterior, RAO right anterior oblique