Fig. 5.

Glycan microheterogeneity can manifest in several different forms. Glycosites can have small or large degrees of glycan heterogeneity, and this level of glycan diversity can even differ for glycosites on the same protein. Here three examples of different modes of heterogeneity are provided: a several glycosites on one protein with limited glycan heterogeneity (Protein sidekick-2), b a protein with one glycosite that has some degree of heterogeneity (SPARC), and c several glycosites on one protein that show either low or high glycan heterogeneity (Na/K-transporting ATPase subunit beta-2)