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. 2019 Mar 21;9:4971. doi: 10.1038/s41598-019-41369-w

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Models’ Spearman’s correlation at increasing IF cut-off thresholds. Box plots of the Spearman’s correlation between the contact maps derived from chromosomal models and the input Hi-C data contact map for each chromosome at increasing IF cut-off threshold 0, 1, 3, 5, 7, 10. Contacts below each threshold are removed and not used in the Spearman correlation calculation for each chromosome. The Spearman’s correlation increases with respect to the increase of the cut-off threshold.