Fig. 3.

Interactions between β-defensin-2, Lactobacillus spp. relative abundance, M. curtisii/mulieris relative abundance, vaginal community state types and pregnancy outcomes in AA women at visit 1. Each woman who went on to deliver preterm is represented by a triangle, while those who delivered at term by a square. Large and small triangles or squares are colored by CSTs and indicate relative abundances (RA) of M. curtisii/mulieris above and below its threshold value, respectively, as defined in Fig. 1. β-defensin-2 concentrations and Lactobacillus spp. relative abundances were stratified into tertiles. The color of each quadrant indicates the proportion of sPTBs (number of sPTB/total births). p-values were estimated using Bayesian binomial models using uniform prior for two proportions implemented in rstan R package