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. 2019 Mar 21;9:5011. doi: 10.1038/s41598-019-41383-y

Table 5.

Full Specification: Final Logistic Model.

i Variable (Vi) Coefficient (Ci) Std. Error Odds Ratio (95% CI)
Intercept −2.7551480
1 Age −0.0379528 0.00663
2 Age2 6.15945E-04 0.00014
3 Age3 −1.04739E-06 8.77732E-07
Gender
4 Female 0.2216384 0.01588 1.248 (1.210,1.288)
Ethnicity
5 Indigenous Australian 0.4033629 0.07675 1.497 (1.288,1.740)
6 Unknown −0.0662497 0.01660 0.936 (0.906,0.967)
BMI
7 [25, 30) 0.0329420 0.02884 1.033 (0.977,1.094)
8 [30, 35) 0.1939825 0.03225 1.214 (1.140,1.293)
9 [35, 40) 0.2712273 0.04200 1.312 (1.208,1.424)
10 40+ 0.4643618 0.04627 1.591 (1.453,1.742)
11 Not recorded 0.1395070 0.02198 1.150 (1.101,1.200)
Smoking Status
12 Ex smoker 0.1969316 0.01761 1.218 (1.176,1.260)
13 Smoker 0.4057213 0.01636 1.500 (1.453,1.549)
14 Unknown 0.1993470 0.02421 1.221 (1.164,1.280)
AnyAlcohol
15 Drinker −0.2853232 0.03423 0.752 (0.703,0.804)
16 Not recorded −0.2301394 0.04245 0.794 (0.731,0.863)
SEIFA IRSAD
17 1 −0.0123849 0.02505 0.988 (0.940,1.037)
18 2 −0.0742180 0.05930 0.928 (0.827,1.043)
19 3 0.0044308 0.03370 1.004 (0.940,1.073)
20 4 −0.1857272 0.02472 0.831 (0.791,0.872)
21 6 −0.2340966 0.02585 0.791 (0.752,0.832)
22 7 −0.2468854 0.02507 0.781 (0.744,0.821)
26 8 −0.2990624 0.02832 0.742 (0.701,0.784)
24 9 −0.1834029 0.02176 0.832 (0.798,0.869)
25 10 −0.4622169 0.02792 0.630 (0.596,0.665)
26 Unknown −0.0301620 0.13850 0.970 (0.740,1.273)
Medications
27 Statins −0.0152881 0.02606 0.985 (0.936,1.036)
28 AntiCoagulants 0.2886091 0.04044 1.335 (1.233,1.445)
29 AntiDepressants 0.2025163 0.03020 1.224 (1.154,1.299)
30 AntiPsychotics 0.3923084 0.03527 1.480 (1.382,1.586)
31 AntiInflammatories 0.1301034 0.01442 1.139 (1.107,1.172)
32 Steroids 0.1488350 0.01800 1.160 (1.120,1.202)
Number of Diagnosis Families
33 Num. Diagnosis Families 0.3369661 0.03298
34 (Num. Diagnosis Families)2 −0.0397663 0.00653
35 (Num. Diagnosis Families)3 0.0019304 0.00057
Diagnosis Groups
36 Respiratory −0.0715037 0.04264 0.931 (0.856,1.012)
37 Atrial Fibrillation 0.2234789 0.05779 1.250 (1.117,1.400)
38 Cardiovascular 0.4764327 0.04877 1.610 (1.464,1.772)
39 Osteoarthritis −0.2060183 0.03764 0.814 (0.756,0.876)
40 Osteoporosis 0.0595034 0.08957 1.061 (0.890,1.265)
41 Rheumatoid Arthritis 0.1149149 0.07502 1.122 (0.968,1.299)
42 Mental Health 0.0686955 0.04483 1.071 (0.981,1.169)
43 Cancer 0.0600825 0.04073 1.062 (0.980,1.150)
44 Digestive Diseases 0.1796635 0.03992 1.197 (1.107,1.294)
45 Hypertension −0.1591489 0.04100 0.853 (0.787,0.924)
46 Bloodfats −0.3726723 0.03771 0.689 (0.640,0.742)
47 Chronic Kidney Disease 0.0268266 0.08500 1.027 (0.870,1.213)
48 Diabetes (type 1) 0.5844975 0.10630 1.794 (1.457,2.210)
49 Diabetes type 2) 0.1332004 0.04722 1.142 (1.041,1.253)
50 Venous Thromboembolism 0.3623621 0.06477 1.437 (1.265,1.631)
51 Other Conditions 0.5157983 0.08211 1.675 (1.426,1.967)
Pathology Test Results
Haemoglobin (g/L)
52 High (<100) 0.4416708 0.06741 1.555 (1.363,1.775)
53 Med (M:100–130, F: 100–120) 0.1546069 0.02639 1.167 (1.108,1.229)
54 No test history 0.0450222 0.17061 1.046 (0.749,1.461)
Platelets (per L)
55 High (>480 × 1e9) 0.1398411 0.08950 1.150 (0.965,1.371)
56 No test history −0.0147097 0.17048 0.985 (0.706,1.376)
Alanine aminotransferase level (u/L)
57 High (M: >120, F: >90) −0.0619518 0.09056 0.940 (0.787,1.122)
58 Med (M: 80–120, F: 60–90) 0.0550267 0.06484 1.057 (0.930,1.200)
29 No test history −0.2940664 0.24315 0.745 (0.463,1.200)
Gamma-glutamyl transferase (u/L)
60 High (M: >150, F: >105) 0.2209109 0.04884 1.247 (1.133,1.372)
61 Med (M: 100–150, F 70–105) 0.1261477 0.04895 1.134 (1.031,1.249)
62 No test history 0.1979201 0.21908 1.219 (0.793,1.873)
Haemoglobin A1c level (mmol/mol)
63 High (〉〉69.4) 0.1746667 0.04153 1.191 (1.098,1.292)
64 Med (58.5–69.4) 0.1720256 0.05061 1.188 (1.076,1.312)
65 No test history −0.0461721 0.01882 0.955 (0.920,0.991)
Total cholesterol (mmol/L)
66 High (>7.5) 0.0453054 0.07726 1.046 (0.899,1.217)
67 Med (6.5–7.5) −0.0363534 0.04640 0.964 (0.880,1.056)
68 No test history 0.1749709 0.15300 1.191 (0.883,1.608)
Albumin/creatinine ratio (mg/mmol)
69 High (>30) 0.3042750 0.08592 1.356 (1.146,1.604)
70 Med (3–30) 0.1151562 0.05232 1.122 (1.013,1.243)
71 No test history 0.1059512 0.02951 1.112 (1.049,1.178)
LDL cholesterol (mmol/L)
72 High (>4) −0.0585925 0.03821 0.943 (0.875,1.016)
73 Med (3–4) −0.0539600 0.02062 0.947 (0.910,0.987)
74 No test history 0.1556545 0.05693 1.168 (1.045,1.306)
Estimated glomerular filtration rate (ml/min)
75 High (<30) 0.0891486 0.07968 1.093 (0.935,1.278)
76 Med (30–45) 0.0950474 0.05205 1.100 (0.993,1.218)
77 No test history 0.0459790 0.02027 1.047 (1.006,1.089)
Blood pressure
78 High (systolic >160 and diastolic >100) 0.2946162 0.10197 1.343 (1.099,1.640)
79 Med (systolic: 140–160 AND diastolic: 90–100) 0.1839175 0.03706 1.202 (1.118,1.292)
80 No test history 0.0112105 0.01543 1.011 (0.981,1.042)
Bilirubin (umol/L)
81 Med_or_High (>40) 0.1803894 0.15242 1.198 (0.888,1.615)
82 No test history 0.0784321 0.21276 1.082 (0.713,1.641)
Creatinine (umol/L)
83 Med_or_High (M: >350, F: >300) 1.1349460 0.15125 3.111 (2.313,4.185)
84 No test history −0.1704331 0.02109 0.843 (0.809,0.879)
Triglycerides (mmol/L)
85 Med_or_High (>4) 0.1234874 0.05878 1.131 (1.008,1.270)
86 No test history −0.0963018 0.16070 0.908 (0.663,1.244)
Gender-Diagnosis Group Interactions Terms
87 Gender × Respiratory 0.0570566 0.04067 1.059 (0.978,1.147)
88 Gender × Cardiovascular −0.2108839 0.05868 0.810 (0.722,0.909)
89 Gender × Osteoporosis −0.2475655 0.09695 0.781 (0.646,0.944)
90 Gender × Mental health −0.0643675 0.03514 0.938 (0.875,1.005)
91 Gender × Hypertension −0.0890935 0.04019 0.915 (0.845,0.990)
92 Gender × Chronic Kidney disease −0.1122160 0.10963 0.894 (0.721,1.108)
93 Gender × Diabetes (type 1) 0.2492323 0.14198 1.283 (0.971,1.695)
94 Gender × Diabetes (type 2) −0.0002784 0.05227 1.000 (0.902,1.108)
95 Gender × Other Conditions −0.1721620 0.10383 0.842 (0.687,1.032)

Note: Coefficients for Age2 and Age3 are shown using scientific notation to provide additional precision.