Figure 6.

Relative contact frequencies of individual residues in the all-parallel orientation CG simulations of M2CD at L/T = 85:1. (A) Contact frequency was calculated as the fraction of snapshots in which a residue was involved in intertetramer contact, and then normalized by the highest value of all residues. (B) The M2CD surface was colored according to residue contact frequency: light blue, low frequency contacts in the TM; dark cyan, midrange contact frequency of the C-terminal portion of the TM segment; dark blue, high-frequency contacts of the amphipathic helix.