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. 2018 Aug 18;10(1):114–121. doi: 10.1016/j.shaw.2018.08.001

Table 5.

Chemical constituents identified which should not be listed as trade secrets by the Korea Occupational Safety and Health Act (KOSHAct), but for which there is no information in the material safety data sheets (MSDSs)

Compound CAS No. Korea MOEL KOSHA IARC ACGIH§ NCIS NTP EU CLP#
Ethylbenzene 100-41-4 Car. 2 Hazardous substances requiring management Group 2B A3
p-Cresol 106-44-5 Hazardous substances requiring management A4 Toxic chemical
1,3-Dimethylbenzene 108-38-3 Hazardous substances requiring management A4 Toxic chemical
1,4-Dioxane 123-91-1 Car. 2 Hazardous substances requiring management Group 2B A3 R Car. 2
2,3-Dimethylphenol 526-75-0 Toxic chemical
3,4-Dimethylphenol 95-65-8 Toxic chemical
Styrene 100-42-5 Car. 2, Repr. 2 Hazardous substances requiring management Group 2A A4 R Repr. 2
2-Butoxyethanol 111-76-2 Car. 2 Hazardous substances requiring management Group 3 A3
2-Heptanone 110-43-0 Hazardous substances requiring management

ACGIH, American Conference of Governmental Industrial Hygienists; CAS, Chemical Abstracts Service; IARC, International Agency for Research on Cancer; KOSHA, Korean Occupational Safety and Health Administration; MOEL, Ministry of Employment and Labor.

*Toxicological information for these ingredients was not specified in the MSDS.

The toxic information of each institute was accessed as follows; Korea MOEL (2018.03.20), ACGIH (2018 booklet), IARC (2018.04.18), NTP (14th report), and EU CLP (Annex vi table 2018).

Ministry Of Employment and Labor, Carcinogen classifications – Carcinogen 1A: Sufficient evidence of carcinogenicity to human, Carcinogen 1B: Sufficient evidence of carcinogenicity to animals or limited evidence of carcinogenicity to human and animals, Carcinogen 2: Insufficient evidence of carcinogenicity to humans and animals.

Korea Occupational Safety and Health Agency – Hazardous substances requiring management should not be designated as trade secrets by KOSHAct.

International Agency for Research on Cancer, Carcinogen classifications – Group 1: Carcinogenic to humans, Group 2A: Probably carcinogenic to humans, Group 2B: Possibly carcinogenic to humans, Group 3: Not classifiable as to its carcinogenicity to humans, Group 4: Probably not carcinogenic to humans.

§

American Conference of Governmental Industrial Hygienists, Carcinogen classifications – A1: Confirmed human carcinogen, A2: Suspected human carcinogen, A3: Confirmed animal carcinogen with unknown relevance to humans, A4: Not classifiable as a human carcinogen, A5: Not suspected as a human carcinogen.

National Chemicals Information System in Korea– Toxic chemical should not be designated as the trade secret by KOSHAct.

National Toxicology Program, Carcinogen classifications – K: Known to be human carcinogens, R: Reasonably anticipated to be human carcinogens.

#

Classification, Labeling, Packing of substances and mixture, Carcinogen classifications – Carcinogen 1A: Known to have carcinogenic potential humans, Carcinogen 1B: May causes cancer, Carcinogen 2: Suspected of causing cancer.