Table 2.
Univariate Cox regression analysis of clinicopathological characteristics influencing the overall survival of HCC patients
| Variables | Univariate | ||
|---|---|---|---|
| HR | 95% CI | P-value | |
| Gender | |||
| Male vs Female | 1.453 | 0.633-3.067 | 0.416 |
| Age (years) | |||
| ≥60 vs <60 | 0.621 | 0.37-1.113 | 0.133 |
| Tumor size (cm) | |||
| ≥5 vs <5 | 1.992 | 1.133-3.503 | 0.017 |
| Vascular invasion | |||
| Positive vs Negative | 3.577 | 1.866-6.855 | <0.001 |
| Pathological stage | |||
| III-IV vs I-II | 1.257 | 0.739-2.204 | 0.388 |
| T stage | |||
| T2-4 vs T1 | 2.247 | 0.894-5.649 | 0.085 |
| TNM stage | |||
| III-IV vs I-II | 2.871 | 1.648-5.003 | <0.001 |
| MMP28 expression | |||
| High vs Low | 2.778 | 1.505-5.129 | <0.001 |
Abbreviations: HR= hazard ratio; 95% CI= 95% confidence interval; P < 0.05 is considered to have statistical significance.