Table 1.
Clinical characteristics of newly diagnosed AML patients
| Characteristics | Median(range) | No. of cases |
|---|---|---|
| Sex | ||
| Female | 14 | |
| Male | 16 | |
| Total | 30 | |
| Median age, y | 55.5(8-79) | |
| Younger than 40 y | 8 | |
| 40-60 y | 9 | |
| Older than 60 y | 13 | |
| Median WBC, 109/L | 44 (0.3-295) | |
| Median platelets, 109/L | 57.3 (3.0 - 655.0) | |
| AML FAB subtype | ||
| AML without maturation: M1 | 3 | |
| AML with maturation: M2 | 7 | |
| Acute promyelocytic leukemia: M3 | 4 | |
| Acute myelomonocytic leukemia: M4 | 5 | |
| Acute monoblastic or monocytic leukemia: M5 | 10 | |
| Other subtypes | 1 | |
| Karyotype | ||
| Normal | 14 | |
| t(8;21) | 3 | |
| t(15;17) | 4 | |
| inv(16) | 7 | |
| Unknown | 2 | |
| Gene mutations | ||
| NPM1 | 14 | |
| FLT3/ITD | 10 | |
| WT1 | 4 | |
| CBFB-MYH11 | 3 |
Abbreviations: AML, acute myeloid leukemia; y, year old; WBC, white blood cell; FAB classification, French-American-British classification, a classification of acute leukemia produced by three-nation joint collaboration.