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. 2019 Mar 20;4(2):e00097-19. doi: 10.1128/mSphere.00097-19

TABLE 2.

Summary of peptide serorecognition comparisons for the domains of three RIFINs and six STEVORs

Surface antigen and serum group No. of peptides recognized (P value)a
Total V1 SC V2
RIFIN
    Adults vs Pediatric
        PF3D7_0833200 143 vs 12*** 19 vs 0** 35 vs 9*** 73 vs 3***
        PF3D7_1041100 114 vs 31*** 3 vs 0 (0.617) 32 vs 17*** 55 vs 13***
        PF3D7_0732400 187 vs 39*** 15 vs 4** 26 vs 16** 120 vs 19***
    Pediatric Infected—day 90 vs day 0
        PF3D7_0833200 99 vs 27*** 15 vs 3 (0.480) 39 vs 13 (0.134) 28 vs 9***
        PF3D7_1041100 88 vs 50** 5 vs 5 (1) 37 vs 23 (0.480) 34 vs 18 (0.077)
        PF3D7_0732400 139 vs 67*** 12 vs 8 (0.131) 30 vs 16*** 77 vs 34**
STEVORs
    Adults vs Pediatric
        PF3D7_1254100 135 vs 40*** 13 vs 1** 80 vs 26*** 17 vs 0***
        PF3D7_0832000 112 vs 1*** 7 vs 0* 54 vs 1*** 27 vs 0***
        PF3D7_0300400 135 vs 38*** 5 vs 0 (0.134) 85 vs 34*** 22 vs 1***
        PF3D7_0115400 132 vs 38*** 4 vs 0 (0.371) 81 vs 31*** 24 vs 4***
        PF3D7_1300900 133 vs 32*** 3 vs 0 (0.617) 80 vs 26*** 22 vs 3***
        PF3D7_0832600 140 vs 10*** 9 vs 1* 80 vs 8*** 29 vs 1***
    Pediatric infected—day 90 vs day 0
        PF3D7_1254100 106 vs 62*** 13 vs 4 (0.248) 71 vs 49** 8 vs 2 (1)
        PF3D7_0832000 64 vs 13*** 1 vs 0 (1) 32 vs 9*** 16 vs 4 (0.617)
        PF3D7_0300400 105 vs 62*** 8 vs 1 (0.617) 67 vs 54** 15 vs 3 (0.134)
        PF3D7_0115400 107 vs 59*** 3 vs 0 (1) 77 vs 28** 13 vs 9 (1)
        PF3D7_1300900 115 vs 58*** 7 vs 0 (1) 79 vs 45*** 13 vs 6*
        PF3D7_0832600 82 vs 23*** 9 vs 1 (0.134) 56 vs 18 *** 5 vs 2 (0.480)
a

*, P < 0.01; **, P < 0.001; ***, P < 0.0001.