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(A) Vasodilatory effect of isoxsuprine in the absence and presence of propranol (1 µM), a β-receptor antagonist. (B) Vasoconstrictor effect of Phenylephrine (Phe) in the absence (control) or presence of isoxsuprine (1 µM) or prazosin (0.12 µM), used as a positive control. Data are means ± SEM (n = 6). Statistical analysis was made using a one-way ANOVA, followed by Dunnett’s post hoc test. Values of *** p < 0.0001 were considered as significant.
