Table 2.
Scoring Subgroup | 0 | 1 | 2 | 3 |
---|---|---|---|---|
Defect filling | No fill | <25% | 25–75% | >75% |
Surface | No surface | Ruptured | Fissured/fibrillated | Meniscus-like |
Integration | No integration | Partial, unilateral integration | Bilateral partial or unilateral complete integration | Bilateral complete integration |
Cellularity | No cells | >10 Cell clusters/slide | No cell clusters/slide, Cell/ECM ratio >0.5 | Meniscus-like cell/ECM ratio |
Cell morphology | No cells | <25% Meniscus-like cells | 25–75% Meniscus-like cells | >75% Meniscus-like cells |
Content of proteoglycan | No staining for proteoglycan | <25% | 25–75% | >75% |
Content of collagen II | No staining for collagen II | <25% | 25–75% | >75% |
Stability | No stability | Weak | Stable in shape | Stable to pressure and pulling stress |
ECM = extracellular matrix.