. 2019 Mar 2;20(5):1080. doi: 10.3390/ijms20051080

Table 3.

Tumor-to-organ ratios 3 h p.i. Female balb/c nu/nu mice with BxPC-3 xenografts were injected with 2 µg of radiolabeled conjugate.

Organ	[⁶⁸Ga]Ga-(HE)₃-Z₀₈₆₉₈-NOTA	[⁶⁸Ga]Ga-Z₀₈₆₉₈-NOTA	[⁶⁸Ga]Ga-(HE)₃-Z₀₈₆₉₈-NODAGA	[⁶⁸Ga]Ga--Z₀₈₆₉₈-NODAGA
Blood	8.5 ± 0.6 ^a,b,c	14 ± 2 ^a,e	15 ± 2 ^b,f	11 ± 1 ^e,f,c
Salivary Glands	2.0 ± 0.1	1.8 ± 0.2	1.8 ± 0.4	1.9 ± 0.2
Lung	2.0 ± 0.2	2.3 ± 0.4	2.0 ± 0.1	2.0 ± 0.2
Liver	0.83 ± 0.10	0.64 ± 0.07 ^d	1.0 ± 0.2 ^d	0.8 ± 0.2
Spleen	5.5 ± 0.8	5.8 ± 0.6	8 ± 1	7.5 ± 0.9
Stomach	2.2 ± 0.2	1.8 ± 0.5	1.7 ± 0.3	1.8 ± 0.5
Small intestine	0.75 ± 0.08	0.8 ±0.4	0.7 ± 0.1	0.7 ± 0.1
Kidney	0.014 ± 0.002 ^b	0.018 ± 0.002 ^d	0.006 ± 0.001 ^b,d,f	0.014 ± 0.003 ^f
Muscle	16 ± 3	20 ± 2	14 ± 1	20 ± 4
Bone	6.0 ± 0.7	9 ± 1	7 ± 5	9 ± 3

Statistical analysis was performed using one-way ANOVA with multiple comparisons using Bonferroni correction. Differences were significant (p < 0.05) between ^a [⁶⁸Ga]Ga-(HE)₃-Z₀₈₆₉₈-NOTA and [⁶⁸Ga]Ga-Z₀₈₆₉₈-NOTA, ^b [⁶⁸Ga]Ga-(HE)₃-Z₀₈₆₉₈-NOTA and [⁶⁸Ga]Ga-(HE)₃-Z₀₈₆₉₈-NODAGA, ^c [⁶⁸Ga]Ga-(HE)₃-Z₀₈₆₉₈-NOTA and [⁶⁸Ga]Ga-Z₀₈₆₉₈-NODAGA, ^d [⁶⁸Ga]Ga-Z₀₈₆₉₈-NOTA and [⁶⁸Ga]Ga-(HE)₃-Z₀₈₆₉₈-NODAGA, ^e [⁶⁸Ga]Ga-Z₀₈₆₉₈-NOTA and [⁶⁸Ga]Ga-Z₀₈₆₉₈-NODAGA, ^f [⁶⁸Ga]Ga-(HE)₃-Z₀₈₆₉₈-NODAGA and [⁶⁸Ga]Ga-Z₀₈₆₉₈-NODAGA.