ADT |
androgen-deprivation therapy |
Akt |
Ak tymoma protein/PKB, protein kinase B |
AR |
androgen receptor |
ATF |
activating transcription factor |
Bax |
Bcl-2-associated X protein |
Bcl-2 |
B-cell lymphoma type 2 protein |
Bcl-XL |
Bcl-2 extra-large protein |
BCRP |
breast cancer resistance protein |
BPH |
benign prostate hyperplasia |
BTG3 |
B-cell translocation gene |
caspase-3 |
cysteine-aspartic acid protease 3 |
CAT |
catalase |
cdc25 |
cell cycle division protein 25 |
CHK1 |
checkpoint kinase 1 |
CHOP |
CCAAT-enhancer-binding protein homologous protein |
c-Met/HGF |
hepatocyte growth factor |
CRPC |
Castration-resistant prostate cancer |
CYP450 |
cytochrome 450 enzymes |
DG5 |
death receptor |
DHT |
dihydrotestosterone |
EGCG |
epigallocatechin gallate |
EGF |
epidermal growth factor |
EGFR |
epidermal growth factor receptor |
ER |
estrogen receptor |
ERK1/2 |
extracelluar signal-regulated kinases -1, -2 |
FoxO |
forkhead box O protein |
GADD153 |
growth arrest and DNA damage inducible protein 153 protein |
GPx |
glutathione peroxidase |
GRB2 |
growth factor receptor-bound protein 2 |
GRP78 |
glucose regulated protein of 78 kDa |
GSK-3β |
glycogen synthase kinase |
GSR |
glutathione reductase |
GSTs |
glutathione-S-transferases |
HER2/ErbB2 |
c-ErbB2 avian erythroblastic leukemia viral homolog 2 |
CXCL-1, -2 |
chemokine with CXC motif ligand -1 -2 |
HSP90 |
heat shock protein 90 |
IGF-1 |
insulin-like growth factor 1 |
IL-6 |
interleukin 6 |
IκB |
inhibitor of NF-κB |
JNK |
c-Jun N-terminal kinase |
LPH |
lactase phloridzin hydrolase |
MAPK |
mitogen activated protein kinase |
miR |
microRNA |
MMP-2 |
matrix metalloproteinase 2 |
MRP |
multidrug resistance-associated protein |
mTOR |
mammalian target of rapamycin |
NF-κB |
nuclear factor kappa-light-chain-enhancer of activated B cells |
OPG |
osteoprotegerin |
p21/CIP1 |
cyclin-dependent kinase inhibitor 1A/CDK-interacting protein 1 |
p27/Kip1 |
kinesin-like protein |
PARP |
poly(ADP-ribose) polymerase |
PDK1 |
phosphoinositide-dependent kinase-1 |
P-gp |
P-glycoprotein |
PI3K |
phosphatidylinositol 3-kinase |
PKC |
protein kinase C |
PSA |
prostate-specific antigen |
PTEN |
phosphatase and tensin homolog |
RARβ |
retinoic acid receptor beta |
ROS |
reactive oxygen species |
SOD |
superoxide dismutase |
SOS |
son of sevenless |
SULTs |
sulphotransferases |
TRAIL |
TNF-related apoptosis-inducing ligand |
TRAMP |
transgenic adenocarcinoma of the mouse prostate |
UGTs |
diphospho-glucuronosyltransferases |
uPA |
urokinase-type plasminogen activator |
VEGF |
vascular endothelial factor; |
c-Jun |
avian sarcoma virus 17 homolog |
ΔΨm
|
mitochondrial membrane potential |