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. 2019 Feb;214(2):83–89. doi: 10.1192/bjp.2018.152

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© The Royal College of Psychiatrists 2018

This is an Open Access article, distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike licence (http://creativecommons.org/licenses/by-nc-nd-sa/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the same Creative Commons licence is included and the original work is properly cited. The written permission of Cambridge University Press must be obtained for commercial re-use.

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Fig. 1 — Immunoglobulin levels in the clozapine-treated and clozapine-naive groups.

The distribution of the serum levels of immunoglobulin (Ig)G, IgA and IgM for the clozapine-treated (light blue, n = 94) and clozapine-naive (dark blue, n = 98) groups are shown with the laboratory 5th and 95th percentile of the reference ranges for a healthy adult population represented as vertical dotted lines. The differences between the median IgG, IgA and IgM levels for the clozapine-treated versus clozapine-naive groups are all significant (P < 0.0001).