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Fully discriminatory biomarker combinations
| Bipolar mood phase | hsCRP/IL-6 | sTNFR1 | BDNF | TNF-α |
|---|---|---|---|---|
| Euthymia | ↑ | ↔ | ↔ | ↔ |
| Depression | ↔ | ↔ | ↓ | ↑ |
| Mania | ↑ | ↑ | ↓ | ↑ |
hsCRP, high-sensitivity C-reactive protein; IL, interleukin; sTNFR1, soluble tumour necrosis factor (TNF)-α receptor 1; BDNF, brain derived neurotrophic factor; ↑, higher in case participants; ↔ , not significantly different from controls; ↓, lower in case participants.
