Table 1.
PCB126 exposure decreased peripheral mean blood flow velocity from 1 nM, caused no change in heart rate but significantly decreased cardiac output. The highest concentration tested (50 nM) could not be measured due to the high reduction of blood cells. Values are mean ± SEM on n = 6 larvae. Asterisks represent statistical significance at * p < 0.05, ** p < 0.01, and *** p < 0.001.
| Treatment | Maximum Blood Flow (nL/min) | Minimum Blood Flow (nL/min) | Heart Rate (beats/min) | Cardiac Output (nL/min) |
|---|---|---|---|---|
| Control | 34.7 ± 6.8 | 5.2 ± 1.1 | 215.7 ± 3.4 | 47.0 ± 6.1 |
| PCB 126 1nM | 12.1 ± 0.7 * | 3.2 ± 0.3 * | 219.4 ± 5.7 | 35.1 ± 4.4 |
| PCB 126 5 nM | 4.7 ± 0.6 * | 0.8 ± 0.1 * | 215.0 ± 10.7 | 22.8 ± 1.4 ** |
| PCB 126 10 nM | 2.7 ± 1.6 * | 0.4 ± 0.3 * | 226.8 ± 17.0 | 14.1 ± 4.7 *** |
| PCB 126 25 nM | 1.7 ± 1.6 * | 0.1 ± 0.1 * | 209.2 ± 5.8 | 22.0 ± 5.9 ** |