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Resveratrol improves pathological aortic features in Marfan syndrome by enhancing beneficial (green) eNOS and miR-21 and decreasing detrimental (red) iNOS, NOX4, ROS, MMP2 and miR-29b. eNOS or iNOS: endothelial or inducible nitric oxide synthase; miR-21 and miR-29b: microRNA-21 and -29b; NOX4: NADPH oxidase 4; ROS: reactive oxygen species; MMP2: matrix metalloproteinase 2.
