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. 2019 Mar 1;24(5):867. doi: 10.3390/molecules24050867

Figure 1.

Figure 1

Effects of 1-O-hexyl-2,3,5-trimethylhydroquinone (HTHQ) on 3,4-l-dihydroxyphenylalanine (l-DOPA)-induced cell viability in PC12 cells. PC12 cells were exposed to l-DOPA (100 and 200 μM) in the absence or presence of HTHQ (1, 10, and 100 μM) for 24 h. The cell viabilities were assessed using the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay, in which visible cells convert the soluble dye MTT to insoluble blue formazan crystals. The results represent the mean ± S.E.M. (n = 4–6). * p < 0.05 compared to the baseline, # p < 0.05 compared to 100 µM l-DOPA-treated group, § p < 0.05 compared to 200 µM l-DOPA-treated group (analysis of variance (ANOVA) with post-hoc Tukey’s test).