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. 2019 Mar 1;24(5):867. doi: 10.3390/molecules24050867

Figure 4.

Figure 4

Effect of HTHQ on l-DOPA-induced p38MAPK (A,B) and JNK1/2 (A,C) phosphorylation in PC12 cells. PC12 cells were exposed to 200 µM l-DOPA (+) in the absence (−) or presence (+) of 10 µM HTHQ for 6 h. The values of the relative density ratios of p38MAPK phosphorylation (p-p38MAPK) to total p38MAPK (t-p38MAPK) and JNK1/2 phosphorylation (p-JNK1/2) to total JNK1/2 (t-JNK1/2) are expressed in arbitrary units. The results are expressed as the mean ± S.E.M. (n = 4). * p < 0.05 compared to l-DOPA-untreated group, # p < 0.05 compared to l-DOPA-treated group (200 μM) (ANOVA with post-hoc Tukey’s test).