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Non-enzymatic oxidation of membrane phospholipids. Free radicals may attack membrane phospholipids such as PAPC, leading to the production of bioactive lipid molecules. Abbreviations: PAPC-OOH, PAPC hydroproxide; OxPC, oxidized phosphatidylcholine; PEIPC, 1-palmitoyl-2-(5,6-epoxyisoprostane E2)-sn-glycero-3-phosphocholine.
