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Enzymatic oxidation of membrane phospholipids. Fatty acids are released from the membrane PL by the phospholipase A2 enzyme and may undergo oxidation through three oxidation pathways including COX, LOX, and CYT P450. Abbreviations: COX, cyclooxygenase; LOX, lipoxygenase; CTY P450, cytochrome P450; HETE; hydroxyeicosatetraenoic acids; EET, epoxyeicosatrienoic acids.
