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Effect of the intracerebroventricular injection of G2-β-CD on motor function in Npc1−/− mice. An injection of G2-β-CD (21.4 μmol/kg) was performed in mice at 4 weeks of age and motor function was evaluated every week up to 10 weeks. Results of the hanging time in the coat hanger test (A) and cage lid test (B). Each point represents the mean ± S.E.M. (n = 6). ** p < 0.01 compared with the saline group.
