Table 5.
Products | Concentration (μM) |
TBARS (nmol/mg prot.) |
Inhibition (%) |
IC50 (μM) |
---|---|---|---|---|
Basal | - | 0.24 ± 0.09 | - | - |
FeSO4 100 µM | - | 9.15 ± 0.32 | - | - |
α-Tocopherol (n = 4) |
0.1 0.32 1 3.16 10 31.62 100 |
6.28 ± 0.18 6.04 ± 0.24 5.21 ± 0.33 * 3.67 ± 0.56 ** 2.72 ± 0.33 ** 1.84 ± 0.31 ** 1.40 ± 0.36 ** |
4.62 ± 0.57 8.26 ± 1.31 21.13 ± 2.56 * 44.84 ± 6.74 ** 59.00 ± 3.71 ** 72.3 ± 3.87 ** 79.09 ± 4.79 ** |
6.78 ± 2.16 |
DAC | 0.1 0.32 1 3.16 10 |
9.68 ± 0.43 9.29 ± 0.67 7.78 ± 0.53 * 5.22 ± 0.35 ** 1.43 ± 0.08 ** |
4.16 ± 1.97 8.32 ± 1.49 23.19 ± 0.92 * 48.46 ± 1.53 ** 85.82 ± 0.60 ** |
3.21 ± 0.16 |
DAC-Cu | 0.1 0.32 1 3.16 10 |
9.08 ± 0.66 8.04 ± 0.70 6.24 ± 0.71 ** 3.08 ± 0.21 ** 1.32 ± 0.48 ** |
10.34 ± 1.48 20.78 ± 2.44 38.70 ± 3.82 ** 69.57 ± 1.56 ** 86.58 ± 5.21 ** |
1.55 ± 0.15 |
DACH4 | 1.78 3.16 5.62 10 17.78 31.62 56.23 |
8.32 ± 0.31 7.85 ± 0.41 * 7.25 ± 0.36 ** 6.32 ± 0.18 ** 4.45 ± 0.22 ** 0.36 ± 0.06 ** 0.14 ± 0.01 ** |
9.05 ± 1.03 14.28 ± 1.59 * 20.86 ± 1.48 ** 30.84 ± 0.57 ** 51.41 ± 0.92 ** 96.02 ± 0.57 ** 98.39 ± 0.18 ** |
16.46 ± 0.30 |
DACH4-Cu | 1.78 3.16 5.62 10 17.78 31.62 56.23 |
7.32 ± 0.30 ** 6.67 ± 0.34 ** 5.89 ± 0.33 ** 3.28 ± 0.37 ** 0.28 ± 0.05 ** 0.20 ± 0.02 ** 0.14 ± 0.007 ** |
19.93 ± 2.01 ** 27.14 ± 1.30 ** 35.74 ± 1.88 ** 64.27 ± 2.74 ** 96.90 ± 0.63 ** 97.73 ± 0.29 ** 98.39 ± 0.03 ** |
7.93 ± 0.41 |
DiMeOC | 17.78 31.62 56.23 100 177.83 |
5.51± 0.13 ** 3.40 ± 0.007 ** 2.67 ± 0.06 ** 2.27 ± 0.09 ** 2.08 ± 0.10 ** |
38.66 ± 3.26 ** 62.16 ± 1.18 ** 70.33 ± 0.63 ** 74.75 ± 0.92 ** 76.91 ± 0.88 ** |
23.01 ± 1.37 |
DiMeOC-Cu | 1 3.16 10 31.62 100 316.23 |
8.58 ± 0.28 7.42 ± 0.20 ** 4.28 ± 0.06 ** 3.10 ± 0.12 ** 2.89 ± 0.16 ** 2.8 0± 0.23 ** |
4.55 ± 4.35 17.51 ± 2.63 ** 52.41 ± 1.20 ** 65.56 ± 1.49 ** 67.90 ± 1.17 ** 68.97 ± 1.99 ** |
9.35 ± 0.34 |
Data presented as mean ± SEM of three replicates. * p ≤ 0.05 and ** p ≤ 0.05 compared to FeSO4.